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Mitochondria-dependent and -independent mechanisms in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis are both regulated by interferon-gamma in human breast tumour cells.

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL/APO-2L) induces apoptosis in a variety of tumour cells upon binding to death receptors TRAIL-R1 and TRAIL-R2. Here we describe the sensitization by interferon (IFN)-gamma to TRAIL-induced apoptosis in the breast tumour cell lines MCF-7...

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Autors principals: Ruiz-Ruiz, Carmen, López-Rivas, Abelardo
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222705/
https://ncbi.nlm.nih.gov/pubmed/11936954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020184
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