A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning.

Zearalenone (ZEN) is converted into a far less oestrogenic product by incubation with Clonostachys rosea IFO 7063. An alkaline hydrolase responsible for the detoxification was purified to homogeneity from the fungus by a combination of salt precipitation and column chromatography methods. The purifi...

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Bibliographic Details
Main Authors: Takahashi-Ando, Naoko, Kimura, Makoto, Kakeya, Hideaki, Osada, Hiroyuki, Yamaguchi, Isamu
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222652/
https://ncbi.nlm.nih.gov/pubmed/11978180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020450
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