TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum.

Until recently, it had been thought that trypanosomes lack glutathione peroxidase activity. Here we report the subcellular localization and biochemical properties of a second glutathione-dependent peroxidase from Trypanosoma cruzi (TcGPXII). TcGPXII is a single-copy gene which encodes a 16 kDa prote...

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Hlavní autoři: Wilkinson, Shane R, Taylor, Martin C, Touitha, Said, Mauricio, Isabel L, Meyer, David J, Kelly, John M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222628/
https://ncbi.nlm.nih.gov/pubmed/12049643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020038
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