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Cytoplasmic domains of the reduced folate carrier are essential for trafficking, but not function.

The reduced folate carrier (RFC) protein has a secondary structure consistent with the predicted 12 transmembrane (TM) domains, intracellular N- and C-termini and a large cytoplasmic loop between TM6 and TM7. In the present study, the role of the cytoplasmic domains in substrate transport and protei...

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Bibliografiske detaljer
Main Authors: Sadlish, Heather, Williams, Frederick M R, Flintoff, Wayne F
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222627/
https://ncbi.nlm.nih.gov/pubmed/12049642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011361
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