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Evidence for the nitration of gamma-tocopherol in vivo: 5-nitro-gamma-tocopherol is elevated in the plasma of subjects with coronary heart disease.

This study investigated the hypothesis that nitration of gamma-tocopherol may be an important mechanism for the detoxification of reactive nitrogen oxide species in vivo. Using liquid chromatography-tandem MS we have shown that gamma-tocopherol can be nitrated in vivo to form 5-nitro-gamma-tocophero...

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Detalhes bibliográficos
Main Authors: Morton, Lincoln W, Ward, Natalie C, Croft, Kevin D, Puddey, Ian B
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222608/
https://ncbi.nlm.nih.gov/pubmed/11960550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020491
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