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Studies on the relevance of the glycan at Asn-52 of the alpha-subunit of human chorionic gonadotropin in the alphabeta dimer.

Glycosylation of Asn-52 of the alpha-subunit (alphaAsn-52) is required for bioactivity of the alphabeta-dimeric human chorionic gonadotropin (hCG), although at a molecular level the effect of the glycan at alphaAsn-52 is not yet understood. To study the role of this glycan for heterodimer stability,...

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Detalles Bibliográficos
Main Authors: Erbel, Paul J A, Haseley, Simon R, Kamerling, Johannis P, Vliegenthart, Johannes F G
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222594/
https://ncbi.nlm.nih.gov/pubmed/12023892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011482
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