Characteristics and composition of the vitamin K-dependent gamma-glutamyl carboxylase-binding domain on osteocalcin.

Two different sites on vitamin K-dependent gamma-glutamyl carboxylase (VKC) are involved in enzyme-substrate interaction: the propeptide-binding site required for high-affinity substrate binding and the active site for glutamate carboxylation. Synthetic descarboxy osteocalcin (d-OC) is a low-K(m) su...

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Bibliografiska uppgifter
Huvudupphovsmän: Houben, Roger J T J, Rijkers, Dirk T S, Stanley, Thomas B, Acher, Francine, Azerad, Robert, Käkönen, Sanna-Maria, Vermeer, Cees, Soute, Berry A M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222576/
https://ncbi.nlm.nih.gov/pubmed/11988107
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