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The murMN operon: A functional link between antibiotic resistance and antibiotic tolerance in Streptococcus pneumoniae

Inactivation of the recently identified murMN operon in penicillin-resistant strains of Streptococcus pneumoniae was shown already to cause two major effects: elimination of branched-structured muropeptides from the cell wall and complete loss of penicillin resistance. We now show that cells with in...

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Autori principali: Filipe, Sergio R., Severina, Elena, Tomasz, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122228/
https://ncbi.nlm.nih.gov/pubmed/11830670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032671699
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