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Allosteric behaviour of 1:5 hybrids of mutant subunits of Clostridium symbiosum glutamate dehydrogenase differing in their amino acid specificity.

Hybrid hexamers were made by refolding mixtures of two mutant forms of clostridial glutamate dehydrogenase. Mutant Cys320Ser (C320S) has a similar activity to the wild-type enzyme, but is unreactive with Ellman's reagent, 5,5'-dithiobis(2-nitrobenzoate) (DTNB). The triple mutant Lys89Leu/A...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Goyal, A, Wang, X G, Engel, P C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222269/
https://ncbi.nlm.nih.gov/pubmed/11736656
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