Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.

Protein kinases of the DYRK ('dual-specificity tyrosine-regulated kinase') family are characterized by a conserved Tyr-Xaa-Tyr motif (Tyr-319-Tyr-321) in a position exactly corresponding to the activation motif of the mitogen-activated protein kinase (MAP kinase) family (Thr-Xaa-Tyr). In a...

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Main Authors: Himpel, S, Panzer, P, Eirmbter, K, Czajkowska, H, Sayed, M, Packman, L C, Blundell, T, Kentrup, H, Grötzinger, J, Joost, H G, Becker, W
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222170/
https://ncbi.nlm.nih.gov/pubmed/11672423
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