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Survival-factor-induced phosphorylation of Bad results in its dissociation from Bcl-x(L) but not Bcl-2.

The pro-apoptotic Bcl-2-family protein Bad heterodimerizes with Bcl-2 and Bcl-x(L) in the outer mitochondrial membranes, nullifying their anti-apoptotic activities and promoting cell death. We report that interleukin-3 (IL-3) stimulation induces Bad phosphorylation and triggers its translocation fro...

詳細記述

保存先:
書誌詳細
主要な著者: Hirai, I, Wang, H G
フォーマット: Artigo
言語:Inglês
出版事項: 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222152/
https://ncbi.nlm.nih.gov/pubmed/11583580
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