Multimerization of monocyte chemoattractant protein-1 is not required for glycosaminoglycan-dependent transendothelial chemotaxis.

Chemokines interact with specific G-protein-coupled cell-surface receptors and with glycosaminoglycans (GAGs), such as heparan sulphate. Although chemokines often form multimers in solution, this process may be enhanced following interaction with GAGs on the cell surface, or within the extracellular...

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Autores principales: Ali, S, Palmer, A C, Fritchley, S J, Maley, Y, Kirby, J A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222107/
https://ncbi.nlm.nih.gov/pubmed/11535134
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