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Assembly of protein kinase CK2: investigation of complex formation between catalytic and regulatory subunits using a zinc-finger-deficient mutant of CK2beta.

Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2beta) and two catalytic subunits (CK2alpha and/or CK2alpha'). The crystal structure of dimeric CK2beta demonstrated that a zinc finger mediates CK2beta dimerization, therefore we constructed a mutant in which cys...

詳細記述

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書誌詳細
主要な著者: Canton, D A, Zhang, C, Litchfield, D W
フォーマット: Artigo
言語:Inglês
出版事項: 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222035/
https://ncbi.nlm.nih.gov/pubmed/11485555
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