Characterization of membrane-localized and cytosolic Rac-GTPase-activating proteins in human neutrophil granulocytes: contribution to the regulation of NADPH oxidase.

We have investigated the intracellular localization and molecular identity of Rac-GTPase-activating proteins (Rac-GAPs) in human neutrophils. Immunoblot analysis detected the presence of both p190RhoGAP and Bcr mainly in the cytosol. An overlay assay performed with [gamma-(32)P]GTP-bound Rac reveale...

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Библиографические подробности
Главные авторы: Geiszt, M, Dagher, M C, Molnár, G, Havasi, A, Faure, J, Paclet, M H, Morel, F, Ligeti, E
Формат: Artigo
Язык:Inglês
Опубликовано: 2001
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221803/
https://ncbi.nlm.nih.gov/pubmed/11311150
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