Interleukin-1beta enhances bradykinin-induced phosphoinositide hydrolysis and Ca2+ mobilization in canine tracheal smooth-muscle cells: involvement of the Ras/Raf/mitogen-activated protein kinase (MAPK) kinase (MEK)/MAPK pathway.

Elevated levels of several cytokines including interleukin-1beta (IL-1beta) have been detected in airway fluid of asthmatic patients. Inhalation of IL-1beta induced a bronchial hyper-reactivity to contractile agonists. However, the implication of IL-1beta in the pathogenesis of bronchial hyper-react...

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Hlavní autoři: Yang, C M, Chien, C S, Wang, C C, Hsu, Y M, Chiu, C T, Lin, C C, Luo, S F, Hsiao, L D
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221673/
https://ncbi.nlm.nih.gov/pubmed/11171124
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