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Drosophila mitochondrial transcription factor A (d-TFAM) is dispensable for the transcription of mitochondrial DNA in Kc167 cells.

We have cloned cDNA encoding Drosophila mitochondrial (mt) transcription factor A (d-TFAM). RNA interference (RNAi) of d-TFAM by lipofection of haemocyte-derived Kc167 cells with double-stranded RNA reduced d-TFAM to less than 5% of the normal level. Reflecting the ability of TFAM to stabilize mtDNA...

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Autores principales: Goto, A, Matsushima, Y, Kadowaki, T, Kitagawa, Y
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221649/
https://ncbi.nlm.nih.gov/pubmed/11171100
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