5-Aminolaevulinate synthase gene promoter contains two cAMP-response element (CRE)-like sites that confer positive and negative responsiveness to CRE-binding protein (CREB).

The first and rate-controlling step of the haem biosynthetic pathway in mammals and fungi is catalysed by the mitochondrial-matrix enzyme 5-aminolaevulinate synthase (ALAS). The purpose of this work was to explore the molecular mechanisms involved in the cAMP regulation of rat housekeeping ALAS gene...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Giono, L E, Varone, C L, Cánepa, E T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2001
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221573/
https://ncbi.nlm.nih.gov/pubmed/11139395
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk