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Defective localization of the Wilson disease protein (ATP7B) in the mammary gland of the toxic milk mouse and the effects of copper supplementation.

Toxic milk (tx) is a copper disorder of mice that causes a hepatic accumulation of copper similar to that seen in patients with Wilson disease. Both disorders are caused by a defect in the ATP7B copper-transporting ATPase. A feature of the tx phenotype is the production of copper-deficient milk by l...

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Main Authors: Michalczyk, A A, Rieger, J, Allen, K J, Mercer, J F, Ackland, M L
Formato: Artigo
Idioma:Inglês
Publicado: 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221490/
https://ncbi.nlm.nih.gov/pubmed/11085952
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