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Induction of prostaglandin endoperoxide synthase 2 by mitogen-activated protein kinase cascades.

Prostaglandin endoperoxide synthase (PGHS) catalyses the rate-limiting step in the formation of prostaglandin and thromboxane eicosanoids from arachidonic acid released by phospholipase A(2). Two forms of PGHS exist, PGHS-1 and PGHS-2. PGHS-2, normally absent from cells, is rapidly expressed in resp...

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Detalles Bibliográficos
Main Authors: McGinty, A, Foschi, M, Chang, Y W, Han, J, Dunn, M J, Sorokin, A
Formato: Artigo
Idioma:Inglês
Publicado: 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221473/
https://ncbi.nlm.nih.gov/pubmed/11085935
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