Dominance of G(s) in doubly G(s)/G(i)-coupled chimaeric A(1)/A(2A) adenosine receptors in HEK-293 cells.

A(1) adenosine receptors inhibit adenylate cyclase by activating G(i)/G(o), whereas A(2A) receptors activate G(s). We examined how regions of A(1) and A(2A) receptors regulate coupling to G-proteins by constructing chimaeras in which the third intracellular loops (3ICL or L) and/or the C-termini (or...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tucker, A L, Jia, L G, Holeton, D, Taylor, A J, Linden, J
Format: Artigo
Langue:Inglês
Publié: 2000
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221448/
https://ncbi.nlm.nih.gov/pubmed/11062074
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires