N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo.

We reported previously that synthetic amides of polyunsaturated fatty acids with bioactive amines can result in substances that interact with proteins of the endogenous cannabinoid system (ECS). Here we synthesized a series of N-acyl-dopamines (NADAs) and studied their effects on the anandamide memb...

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Bibliographische Detailangaben
Hauptverfasser: Bisogno, T, Melck, D, Bobrov MYu, Gretskaya, N M, Bezuglov, V V, De Petrocellis, L, Di Marzo, V
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221424/
https://ncbi.nlm.nih.gov/pubmed/11042139
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