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Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy.

Plasmodium, the aetiologic agent of malaria, cannot synthesize purines de novo, and hence depends upon salvage from the host. Here we describe the molecular cloning and functional expression in Xenopus oocytes of the first purine transporter to be identified in this parasite. This 422-residue protei...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Parker, M D, Hyde, R J, Yao, S Y, McRobert, L, Cass, C E, Young, J D, McConkey, G A, Baldwin, S A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221121/
https://ncbi.nlm.nih.gov/pubmed/10861212
Etiketak: Etiketa erantsi
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