Repression of transforming-growth-factor-beta-mediated transcription by nuclear factor kappaB.

Activation of transforming growth factor-beta (TGF-beta) and activin receptors leads to phosphorylation of Sma- and Mad-related protein 2 (Smad2) and Smad3, which function as transcription factors to regulate gene expression. Smad7 is a regulatory protein which is able to inhibit TGF-beta and activi...

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Bibliographic Details
Main Authors: Nagarajan, R P, Chen, F, Li, W, Vig, E, Harrington, M A, Nakshatri, H, Chen, Y
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221102/
https://ncbi.nlm.nih.gov/pubmed/10839991
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