The ShBle resistance determinant from Streptoalloteichus hindustanus is expressed in Haloferax volcanii and confers resistance to bleomycin.

We have designed a gene cassette for expression of the bleomycin-resistance protein from Streptoalloteichus hindustanus (ShBle) in the extremely halophilic archaeon Haloferax volcanii, and shown that transformed haloarchaea are resistant to bleomycin. Recombinant ShBle was purified by a one-step aff...

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Autors principals: Nuttall, S D, Deutschel, S E, Irving, R A, Serrano-Gomicia, J A, Dyall-Smith, M L
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220848/
https://ncbi.nlm.nih.gov/pubmed/10677341
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