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Identification of structurally important domains of lipid phosphate phosphatase-1: implications for its sites of action.

Lipid phosphate phosphatase-1 (LPP-1) dephosphorylates exogenous lysophosphatidate and thereby regulates the activation of lysophosphatidate receptors and cell division. Mutation of seven amino acids in three conserved domains of mouse LPP-1 abolished its activity. A glycosylation site was demonstra...

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Autors principals: Zhang, Q X, Pilquil, C S, Dewald, J, Berthiaume, L G, Brindley, D N
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220744/
https://ncbi.nlm.nih.gov/pubmed/10620492
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