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Truncated isoforms inhibit [3H]prazosin binding and cellular trafficking of native human alpha1A-adrenoceptors.

We have identified from human liver eight alpha(1A)-adrenoceptor (alpha(1A)-AR) splice variants that were also expressed in human heart, prostate and hippocampus. Three of these alpha(1A)-AR isoforms (alpha(1A-1)-AR, alpha(1A-2a)-AR and alpha(1A-3a)-AR) gave rise to receptors with seven transmembran...

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Autors principals: Cogé, F, Guenin, S P, Renouard-Try, A, Rique, H, Ouvry, C, Fabry, N, Beauverger, P, Nicolas, J P, Galizzi, J P, Boutin, J A, Canet, E
Format: Artigo
Idioma:Inglês
Publicat: 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220546/
https://ncbi.nlm.nih.gov/pubmed/10493934
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