Signal transduction pathway regulating prostaglandin EP3 receptor-induced neurite retraction: requirement for two different tyrosine kinases.

We reported previously that activation of the prostaglandin E receptor EP3 subtype triggered neurite retraction through the small GTPase Rho-, and its target, RhoA-binding kinase alpha (ROKalpha)-, dependent pathway in EP3 receptor-expressing PC12 cells. Here we examined the involvement of tyrosine...

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Hauptverfasser: Aoki, J, Katoh, H, Yasui, H, Yamaguchi, Y, Nakamura, K, Hasegawa, H, Ichikawa, A, Negishi, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220258/
https://ncbi.nlm.nih.gov/pubmed/10333476
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