Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1.

Centaurin-alpha is a 46 kDa in vitro binding protein for the lipid second messenger PtdIns(3,4,5)P3. In this report we have addressed whether centaurin-alpha1, a human homologue of centaurin-alpha, binds PtdIns(3,4,5)P3 in vivo and furthermore, identified a potential physiological function for centa...

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Detalles Bibliográficos
Main Authors: Venkateswarlu, K, Oatey, P B, Tavaré, J M, Jackson, T R, Cullen, P J
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220257/
https://ncbi.nlm.nih.gov/pubmed/10333475
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