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Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling.

Fibrillin is the principal structural component of the 10-12 nm diameter elastic microfibrils of the extracellular matrix. We have previously shown that both fibrillin molecules and assembled microfibrils are susceptible to degradation by serine proteases. In this study, we have investigated the pot...

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Detalhes bibliográficos
Main Authors: Ashworth, J L, Murphy, G, Rock, M J, Sherratt, M J, Shapiro, S D, Shuttleworth, C A, Kielty, C M
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220235/
https://ncbi.nlm.nih.gov/pubmed/10229672
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