Purified meningococcal transferrin-binding protein B interacts with a secondary, strain-specific, binding site in the N-terminal lobe of human transferrin.

Neisseria meningitidis, grown in iron-limited conditions, produces two transferrin-binding proteins (TbpA and TbpB) that independently and specifically bind human serum transferrin (hTF) but not bovine serum transferrin (bTF). We have used surface plasmon resonance to characterize the interaction be...

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Detalhes bibliográficos
Main Authors: Boulton, I C, Gorringe, A R, Gorinsky, B, Retzer, M D, Schryvers, A B, Joannou, C L, Evans, R W
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220138/
https://ncbi.nlm.nih.gov/pubmed/10085238
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