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Structural aspects of the effectiveness of bisphosphonates as competitive inhibitors of the plant vacuolar proton-pumping pyrophosphatase.

The bisphosphonates (general structure PO3-R-PO3) competitively inhibit soluble and membrane-bound inorganic pyrophosphatases (PPases) with differing degrees of specificity. Aminomethylenebisphosphonate (AMBP; HC(PO3)2NH2) is a potent, specific inhibitor of the PPase of higher plant vacuoles (V-PPas...

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Bibliografiska uppgifter
Huvudupphovsmän: Gordon-Weeks, R, Parmar, S, Davies, T G, Leigh, R A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1999
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219987/
https://ncbi.nlm.nih.gov/pubmed/9895279
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