Changes in polyamine catabolism in HL-60 human promyelogenous leukaemic cells in response to etoposide-induced apoptosis.

The topoisomerase II inhibitor etoposide induced apoptosis in HL-60 cells within 4 h of exposure to the drug, as measured by changes in morphology, DNA fragmentation and cytotoxicity assays. Etoposide-induced apoptosis was accompanied by an increase in polyamine efflux from the cells and a decrease...

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Hlavní autoři: Lindsay, G S, Wallace, H M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219939/
https://ncbi.nlm.nih.gov/pubmed/9854028
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