Increased bioactivation of dihaloalkanes in rat liver due to induction of class theta glutathione S-transferase T1-1.

A characteristic feature of the class Theta glutathione S-transferase (GST) T1-1 is its ability to activate dichloromethane and dibromoethane by catalysing the formation of mutagenic conjugates. The level of the GSTT1 subunit within tissues is an important determinant of susceptibility to the carcin...

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Detalhes bibliográficos
Main Authors: Sherratt, P J, Manson, M M, Thomson, A M, Hissink, E A, Neal, G E, van Bladeren, P J, Green, T, Hayes, J D
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219824/
https://ncbi.nlm.nih.gov/pubmed/9794803
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