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alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state.

The mechanism of protein kinase C (PKC) regulation by alpha-tocopherol has been investigated in smooth-muscle cells. Treatment of rat aortic A7r5 smooth-muscle cells with alpha-tocopherol resulted in a time- and dose-dependent inhibition of PKC. The inhibition was not related to a direct interaction...

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Dettagli Bibliografici
Autori principali: Ricciarelli, R, Tasinato, A, Clément, S, Ozer, N K, Boscoboinik, D, Azzi, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219685/
https://ncbi.nlm.nih.gov/pubmed/9693126
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