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Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 protein.

The role of protein tyrosine kinase activity in ErbB3-mediated signal transduction was investigated. ErbB3 was phosphorylated in vivo in response to either heregulin (HRG) in cells expressing both ErbB3 and ErbB2, or epidermal growth factor (EGF) in cells expressing both ErbB3 and EGF receptor. A re...

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Autori principali: Kim, H H, Vijapurkar, U, Hellyer, N J, Bravo, D, Koland, J G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219678/
https://ncbi.nlm.nih.gov/pubmed/9693119
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