Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes.

The expression of the rate-limiting enzyme of haem degradation, haem oxygenase-1 (HO-1), can be induced by various stimuli, including lipopolysaccharide, tumour necrosis factor alpha and NO. The NO signal can be transmitted by cGMP, therefore this study was aimed at testing the activation of the HO-...

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Detalhes bibliográficos
Main Authors: Immenschuh, S, Hinke, V, Ohlmann, A, Gifhorn-Katz, S, Katz, N, Jungermann, K, Kietzmann, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219672/
https://ncbi.nlm.nih.gov/pubmed/9693113
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