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Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1.

Thrombin is a multifunctional serine protease that has a crucial role in blood coagulation. It is also a potent mesenchymal cell mitogen and chemoattractant and might therefore have an important role in the recruitment and local proliferation of mesenchymal cells at sites of tissue injury. We hypoth...

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Main Authors: Chambers, R C, Dabbagh, K, McAnulty, R J, Gray, A J, Blanc-Brude, O P, Laurent, G J
格式: Artigo
語言:Inglês
出版: 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219564/
https://ncbi.nlm.nih.gov/pubmed/9639571
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