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Reactions of nitric oxide with mitochondrial cytochrome c: a novel mechanism for the formation of nitroxyl anion and peroxynitrite.

The aerobic reactions of nitric oxide with cytochrome c were analysed. Nitric oxide (NO) reacts with ferrocytochrome c at a rate of 200 M-1 s-1 to form ferricytochrome c and nitroxyl anion (NO-). Ferricytochrome c was detected by optical spectroscopy; NO- was detected by trapping with metmyoglobin (...

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Sonraí Bibleagrafaíochta
Main Authors: Sharpe, M A, Cooper, C E
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1998
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219446/
https://ncbi.nlm.nih.gov/pubmed/9576846
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