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Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.
The regulatory and catalytic properties of the three mammalian isoforms of protein kinase B (PKB) have been compared. All three isoforms (PKBalpha, PKBbeta and PKBgamma) were phosphorylated at similar rates and activated to similar extents by 3-phosphoinositide-dependent protein kinase-1 (PDK1). Pho...
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Main Authors: | , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
1998
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1219352/ https://ncbi.nlm.nih.gov/pubmed/9512493 |
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