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Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

The regulatory and catalytic properties of the three mammalian isoforms of protein kinase B (PKB) have been compared. All three isoforms (PKBalpha, PKBbeta and PKBgamma) were phosphorylated at similar rates and activated to similar extents by 3-phosphoinositide-dependent protein kinase-1 (PDK1). Pho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Walker, K S, Deak, M, Paterson, A, Hudson, K, Cohen, P, Alessi, D R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219352/
https://ncbi.nlm.nih.gov/pubmed/9512493
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