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Contribution of newly synthesized cholesterol to rat plasma and bile determined by mass isotopomer distribution analysis: bile-salt flux promotes secretion of newly synthesized cholesterol into bile.

To quantify the contribution of newly synthesized cholesterol to total plasma and biliary cholesterol under physiological conditions, unrestrained rats were infused intravenously with [1-13C]acetate (0. 6mmol/h per kg) from 12:00 to 24:00 h, and fractional and absolute cholesterol-synthesis rates we...

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Detalhes bibliográficos
Main Authors: Bandsma, R H, Stellaard, F, Vonk, R J, Nagel, G T, Neese, R A, Hellerstein, M K, Kuipers, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219095/
https://ncbi.nlm.nih.gov/pubmed/9445401
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