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Capacity for repeatable leukotriene generation after transient stimulation of mast cells and macrophages.

Leukotriene (LT) synthesis is initiated by the enzyme 5-lipoxygenase (5-LO). Prolonged cell stimulation causes the translocation of 5-LO to the nuclear envelope and the synthesis of LT, with subsequent inactivation and persistent membrane association of 5-LO. In this study, we examined whether persi...

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Detalhes bibliográficos
Main Authors: Brock, T G, McNish, R W, Peters-Golden, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219072/
https://ncbi.nlm.nih.gov/pubmed/9445378
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