The two phenylalanines in the GFFKR motif of the integrin alpha6A subunit are essential for heterodimerization.

The membrane-proximal domain of the integrin alpha subunit contains a conserved motif of five amino acid residues, GFFKR. We deleted this motif from the human alpha6A subunit and found that in COS-7 cells this mutant cannot associate with the beta1 subunit and is retained in the endoplasmic reticulu...

Full description

Saved in:
Bibliographic Details
Main Authors: De Melker, A A, Kramer, D, Kuikman, I, Sonnenberg, A
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218952/
https://ncbi.nlm.nih.gov/pubmed/9371712
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items