Superagonistic behaviour of epidermal growth factor/transforming growth factor-alpha chimaeras: correlation with receptor routing after ligand-induced internalization.

Human epidermal growth factor (EGF) and human transforming growth factor alpha (TGF-alpha) are structurally related polypeptide growth factors that exert their mitogenic activity through interaction with a common cell-surface receptor, the epidermal growth factor receptor (EGFR). The biological effe...

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Detalhes bibliográficos
Main Authors: Lenferink, A E, Kramer, R H, van Vugt, M J, Königswieser, M, Di Fiore, P P, van Zoelen, E J, van de Poll, M L
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218868/
https://ncbi.nlm.nih.gov/pubmed/9581567
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