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Comparative anatomy of the aldo-keto reductase superfamily.

The aldo-keto reductases metabolize a wide range of substrates and are potential drug targets. This protein superfamily includes aldose reductases, aldehyde reductases, hydroxysteroid dehydrogenases and dihydrodiol dehydrogenases. By combining multiple sequence alignments with known three-dimensiona...

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Detalhes bibliográficos
Main Authors: Jez, J M, Bennett, M J, Schlegel, B P, Lewis, M, Penning, T M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218714/
https://ncbi.nlm.nih.gov/pubmed/9307009
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