Alternative splicing of ClC-6 (a member of the CIC chloride-channel family) transcripts generates three truncated isoforms one of which, ClC-6c, is kidney-specific.

ClC-6 is a protein that structurally belongs to the family of ClC-type chloride channels. We now report the identification of three additional ClC-6 isoforms that are truncated because of alternative splicing. We have isolated, from human K562 cells, four types of ClC-6 cDNAs that encode four distin...

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Détails bibliographiques
Auteurs principaux: Eggermont, J, Buyse, G, Voets, T, Tytgat, J, De Smedt, H, Droogmans, G, Nilius, B
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218554/
https://ncbi.nlm.nih.gov/pubmed/9224655
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