Rat basophilic leukaemia (RBL) cells overexpressing Rab3a have a reversible block in antigen-stimulated exocytosis.

The rat basophilic leukaemia (RBL) cell line has been widely used as a convenient model system to study regulated secretion in mast cells. Activation of these cells through the high-affinity receptor for IgE (Fcepsilon-RI) results in degranulation and the extracellular release of mediators. There is...

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Bibliografiske detaljer
Main Authors: Smith, J, Thompson, N, Thompson, J, Armstrong, J, Hayes, B, Crofts, A, Squire, J, Teahan, C, Upton, L, Solari, R
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218322/
https://ncbi.nlm.nih.gov/pubmed/9163319
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