Nicotinamide inhibits cyclic ADP-ribose-mediated calcium signalling in sea urchin eggs.

Cyclic ADP ribose (cADPR) is a potent Ca(2+)-releasing agent, and putative second messenger, the endogenous levels of which are tightly regulated by synthetic (ADP-ribosyl cyclases) and degradative (cADPR hydrolase) enzymes. These enzymes have been characterized in a number of mammalian and inverteb...

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Bibliographic Details
Main Authors: Sethi, J K, Empson, R M, Galione, A
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217811/
https://ncbi.nlm.nih.gov/pubmed/8912702
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