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Structural specificity effects of trivalent polyamine analogues on the stabilization and conformational plasticity of triplex DNA.

Natural polyamines, i.e. putrescine, spermidine and spermine, are excellent promoters of triplex DNA. Using melting temperature (Tm) measurements and CD spectroscopy, we found that structural alterations on spermidine backbone, including methylation, or acetylation at the N1-, N4- and/or N8-position...

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Bibliografske podrobnosti
Main Authors: Thomas, T J, Kulkarni, G D, Greenfield, N J, Shirahata, A, Thomas, T
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217808/
https://ncbi.nlm.nih.gov/pubmed/8912699
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