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The folding and activity of the extracellular lipase of Rhizopus oryzae are modulated by a prosequence.

The fungus Rhizopus oryzae synthesizes an extracellular lipase precursor bearing N-terminal pre- and pro-sequences. Our studies in Escherichia coli and using recombinant lipase in vitro indicate that the prosequence of 97 amino acids has at least two functions. First, it modulates the enzyme activit...

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Main Authors: Beer, H D, Wohlfahrt, G, Schmid, R D, McCarthy, J E
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217776/
https://ncbi.nlm.nih.gov/pubmed/8912667
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